Ondrejcak T, Hu NW, Coode E, Campbell T, Corbett GT, Doykov I, Mills K, Walsh DM, Livesey FJ, Rowan MJ, Klyubin I. (2025) Synaptotoxic effects of extracellular tau are mediated by its microtubule-binding region. Acta Neuropathol.  doi: 10.1007/s00401-025-02897-0.

 

Hu NW, Ondrejcak T, Klyubin I, Yang Y, Walsh DM, Livesey FJ, Rowan MJ. (2024) Patient-derived tau and amyloid-β facilitate long-term depression in vivo: role of tumour necrosis factor-α and the integrated stress response. Brain Commun. doi: 10.1093/braincomms/fcae333.

 

Ondrejcak T, Klyubin I, Hu NW, Yang Y, Zhang Q, Rodriguez BJ, Rowan MJ. (2024) Rapidly reversible persistent long-term potentiation inhibition by patient-derived brain tau and amyloid ß proteins. Philos Trans R Soc Lond B Biol Sci. doi: 10.1098/rstb.2023.0234.

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Ondrejcak T, Klyubin I, Hu NW, O'Malley TT, Corbett GT, Winters R, Perkinton MS, Billinton A, Prenderville JA, Walsh DM, Rowan MJ. (2023) Tau and Amyloid β Protein in Patient-Derived Aqueous Brain Extracts Act Concomitantly to Disrupt Long-Term Potentiation in Vivo. J Neurosci. doi: 10.1523/JNEUROSCI.0082-23.2023.

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Hu Z, Ondrejcak T, Yu P, Zhang Y, Yang Y, Klyubin I, Kennelly SP, Rowan MJ, Hu NW. (2023) Do tau-synaptic long-term depression interactions in the hippocampus play a pivotal role in the progression of Alzheimer's disease? Neural Regen Res.  doi: 10.4103/1673-5374.360166.

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Hu Z, Yu P, Zhang Y, Yang Y, Zhu M, Qin S, Xu JT, Duan D, Wu Y, Wang D, Rowan MJ, Hu NW. (2022) Inhibition of the ISR abrogates mGluR5-dependent long-term depression and spatial memory deficits in a rat model of Alzheimer's disease. Transl Psychiatry. doi: 10.1038/s41398-022-01862-9.

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Zhang Y, Yang Y, Hu Z, Zhu M, Qin S, Yu P, Li B, Xu J, Ondrejcak T, Klyubin I, Rowan MJ, Hu NW. (2022) Long-Term Depression-Inducing Low Frequency Stimulation Enhances p-Tau181 and p-Tau217 in an Age-Dependent Manner in Live Rats. J Alzheimers Dis. doi: 10.3233/jad-220351

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Hu NW, Corbett GT, Moore S, Klyubin I, O'Malley TT, Walsh DM, Livesey FJ, Rowan MJ. (2018) Extracellular Forms of Aβ and Tau from iPSC Models of Alzheimer's Disease Disrupt Synaptic Plasticity. Cell Rep. doi: 10.1016/j.celrep.2018.04.040

 

O'Riordan KJ, Hu NW, Rowan MJ. (2018) Aß Facilitates LTD at Schaffer Collateral Synapses Preferentially in the Left Hippocampus. Cell Rep. doi: 10.1016/j.celrep.2018.01.085.

 

Hu NW, Nicoll AJ, Zhang D, Mably AJ, O'Malley T, Purro SA, Terry C, Collinge J, Walsh DM, Rowan MJ. (2014) mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo. Nat Commun.  doi: 10.1038/ncomms4374.

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Hu NW, Klyubin I, Anwyl R, Rowan MJ. (2009) GluN2B subunit-containing NMDA receptor antagonists prevent Aβ-mediated synaptic plasticity disruption in vivo. Proc Natl Acad Sci USA. doi: 10.1073/pnas.0908083106